Sapienic acid sodium ( —— )

产品货号. M26431 CAS No. 217477-25-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Sapienic acid sodium
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

皂酸钠通常是一种脂肪酸。它对皮肤和口腔中的革兰氏阳性和革兰氏阴性细菌具有不同的抗菌活性。
产品描述

Sapienic acid sodium is a fatty acid commonly. It has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity.(In Vitro):Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum. Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h.
体外实验

Sapienic acid (minimum bactericidal concentrations (MBCs) range, 31.3 to 375.0 μg/mL) is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum but not active against Escherichia coli, Staphylococcus aureus, S. marcescens, P. aeruginosa, Corynebacterium bovis, Corynebacterium striatum, and Corynebacterium jeikeium (MBC > 500 μg/mL). Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

BRAG2
研究领域

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适应症

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1.Nawrotek A, et al. PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling. Nat Chem Biol. 2019 Feb 11.

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